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Literature DB >> 1003563

Chemotactic response of leukocytes to cord factor (trehalose-6,6'-dimycolate).

Abstract

Cord factor (trehalose-6,6'-dimycolate), a glycolipid extractable from myocobacteria, was chemotactic for peritoneal cells of mice at concentrations from 5 to 25 mug/ml medium, as well as for peripheral white blood cells of mice and humans. At higher concentrations, presumably only macrophages were attracted.

Entities: Chemical Species

Mesh：

Substances：
Cord Factors
Glycolipids

Year: 1976 PMID： 1003563 DOI： 10.1093/jnci/57.6.1379

Source DB: PubMed Journal: J Natl Cancer Inst ISSN： 0027-8874 Impact factor: 13.506

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Cited

7 in total

1. Mycobacterial glycolipid cord factor trehalose 6,6'-dimycolate causes a decrease in serum cortisol during the granulomatous response.

Authors: Jeffrey K Actor; Jessica Indrigo; Christopher M Beachdel; Margaret Olsen; Alice Wells; Robert L Hunter; Amitava Dasgupta
Journal: Neuroimmunomodulation Date: 2002 -2003 Impact factor: 2.492

2. Neopeptide antibiotics that function as opsonins and membrane-permeabilizing agents for gram-negative bacteria.

Authors: Haim Tsubery; Hertzig Yaakov; Sofia Cohen; Tal Giterman; Ariella Matityahou; Mati Fridkin; Itzhak Ofek
Journal: Antimicrob Agents Chemother Date: 2005-08 Impact factor: 5.191

3. Granuloma formation and hemopoiesis induced by C36-48-mycolic acid-containing glycolipids from Nocardia rubra.

Authors: K Kaneda; Y Sumi; F Kurano; Y Kato; I Yano
Journal: Infect Immun Date: 1986-12 Impact factor: 3.441

4. Proliferative responses of central and peripheral rat lymphocytes elicited by cord factor (trehalose 6,6'-dimycolate).

Authors: F Kierszenbaum; D R Walz
Journal: Infect Immun Date: 1981-07 Impact factor: 3.441

Chemotactic response of leukocytes to cord factor (trehalose-6,6'-dimycolate).

1. Mycobacterial glycolipid cord factor trehalose 6,6'-dimycolate causes a decrease in serum cortisol during the granulomatous response.

2. Neopeptide antibiotics that function as opsonins and membrane-permeabilizing agents for gram-negative bacteria.

3. Granuloma formation and hemopoiesis induced by C36-48-mycolic acid-containing glycolipids from Nocardia rubra.

4. Proliferative responses of central and peripheral rat lymphocytes elicited by cord factor (trehalose 6,6'-dimycolate).

5. Stimulation of macrophages by cord factor and by heat-killed and living BCG.

6. Antitumor activity of mycobacterial glycolipid A1.

7. Interstitial and hemorrhagic pneumonitis induced by mycobacterial trehalose dimycolate.