| Literature DB >> 1003266 |
Abstract
Homozygous Gunn rats, mutant Wistars genetically lacking glucuronyl transferase, develop renal papillary necrosis after single oral doses of aspirin and of phenacetin. The lesion appears significantly more frequently with aspirin than phenacetin, and at lower doses. The model is a convenient one with which to study analgesic nephrotoxicity.Entities:
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Year: 1976 PMID： 1003266 DOI： 10.1002/path.1711200303
Source DB: PubMed Journal: J Pathol ISSN： 0022-3417 Impact factor: 7.996