Literature DB >> 10030568

Resolution of microsporidial sinusitis and keratoconjunctivitis by itraconazole treatment.

P Rossi1, C Urbani, G Donelli, E Pozio.   

Abstract

PURPOSE: To report successful treatment of ocular infection caused by the microsporidium Encephalitozoon cuniculi in a person with acquired immunodeficiency syndrome (AIDS) and nasal and paranasal sinus infection.
METHOD: Case report.
RESULTS: Microsporidial infection in a person with AIDS and with chronic sinusitis and keratoconjunctivitis was diagnosed by Weber modified trichrome stain and transmission electron microscopy. Symptoms completely resolved with itraconazole treatment (200 mg/day for 8 weeks) after albendazole therapy (400 mg/day for 6 weeks) was unsuccessful.
CONCLUSION: Itraconazole can be recommended in ocular, nasal, and paranasal sinus infection caused by E. cuniculi parasites when treatment with albendazole fails.

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Year:  1999        PMID: 10030568     DOI: 10.1016/s0002-9394(98)00352-3

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  6 in total

1.  Demographic and clinical profile of microspodial keratitis in North India: an underreported entity.

Authors:  Sumeeta Khurana; Sonu Kumari Agrawal; Kirti Megha; Sujata Dwivedi; Neha Jain; Amit Gupta
Journal:  J Parasit Dis       Date:  2019-06-15

2.  Microsporidian species known to infect humans are present in aquatic birds: implications for transmission via water?

Authors:  Anna Slodkowicz-Kowalska; Thaddeus K Graczyk; Leena Tamang; Szymon Jedrzejewski; Andrzej Nowosad; Piotr Zduniak; Piotr Solarczyk; Autumn S Girouard; Anna C Majewska
Journal:  Appl Environ Microbiol       Date:  2006-07       Impact factor: 4.792

Review 3.  Importance of nonenteric protozoan infections in immunocompromised people.

Authors:  J L N Barratt; J Harkness; D Marriott; J T Ellis; D Stark
Journal:  Clin Microbiol Rev       Date:  2010-10       Impact factor: 26.132

4.  The Development of Keratopathy after Surgery-Indicated Chronic Rhinosinusitis: A Population-Based Cohort Study.

Authors:  Hung-Jui Hsu; Chia-Yi Lee; Kun-Lin Yang; Hung-Chi Chen; Chi-Chin Sun; Jing-Yang Huang; Hung-Yu Lin; Shun-Fa Yang
Journal:  Int J Environ Res Public Health       Date:  2019-04-05       Impact factor: 3.390

5.  Medical management approach to infectious keratitis.

Authors:  Nikhil S Gokhale
Journal:  Indian J Ophthalmol       Date:  2008 May-Jun       Impact factor: 1.848

Review 6.  A Narrative Review of Microsporidial Infections of the Cornea.

Authors:  Majid Moshirfar; Shaan N Somani; Kathryn M Shmunes; Ladan Espandar; Nikhil S Gokhale; Yasmyne C Ronquillo; Phillip C Hoopes
Journal:  Ophthalmol Ther       Date:  2020-03-10
  6 in total

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