Literature DB >> 10030346

Leprosy.

R R Jacobson1, J L Krahenbuhl.   

Abstract

Leprosy is an ancient disease which is still poorly understood and often feared by the general public and even by some healthcare professionals. Fortunately, improvements in the management of leprosy over the past three decades have diminished the stigma and greatly altered the outlook for patients. Public understanding of the disease has benefited from WHO's goal of eliminating leprosy as a public health problem by the year 2000. Unfortunately that goal has also led many to believe that leprosy has been or will soon be eradicated. This will not happen in the near future because, despite a fall in registered cases, the incidence of the disease has changed very little, and eradication of a bacterial infectious disease such as this is unlikely with chemotherapy alone. Nevertheless, as a result of the WHO's efforts, patients nearly everywhere should have access to care, and the incidence may begin to diminish if adequate control efforts are maintained beyond the year 2000. Given the mobility of patients today a physician anywhere may occasionally see a case or be asked about the disease so a basic understanding of leprosy and its management should prove useful.

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Year:  1999        PMID: 10030346     DOI: 10.1016/S0140-6736(98)06322-3

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  22 in total

Review 1.  Taxonomy, Physiology, and Natural Products of Actinobacteria.

Authors:  Essaid Ait Barka; Parul Vatsa; Lisa Sanchez; Nathalie Gaveau-Vaillant; Cedric Jacquard; Jan P Meier-Kolthoff; Hans-Peter Klenk; Christophe Clément; Yder Ouhdouch; Gilles P van Wezel
Journal:  Microbiol Mol Biol Rev       Date:  2015-11-25       Impact factor: 11.056

2.  [Tuberculoid leprosy ("Single skin lesion")].

Authors:  J Rieker; S Ritzmann; C Talhari; B Homey; T Ruzicka; D Bruch-Gerharz
Journal:  Hautarzt       Date:  2005-10       Impact factor: 0.751

Review 3.  Leprosy: steps along the journey of eradication.

Authors:  Brian H Bennett; David L Parker; Mark Robson
Journal:  Public Health Rep       Date:  2008 Mar-Apr       Impact factor: 2.792

Review 4.  Genomics of Actinobacteria: tracing the evolutionary history of an ancient phylum.

Authors:  Marco Ventura; Carlos Canchaya; Andreas Tauch; Govind Chandra; Gerald F Fitzgerald; Keith F Chater; Douwe van Sinderen
Journal:  Microbiol Mol Biol Rev       Date:  2007-09       Impact factor: 11.056

5.  Analysis of facial deformities in korean leprosy.

Authors:  Ji Heui Kim; Ok Joo Lee; Jae Jun Lee; Chan Hum Park
Journal:  Clin Exp Otorhinolaryngol       Date:  2013-06-14       Impact factor: 3.372

Review 6.  Leprosy and the human genome.

Authors:  Elizabeth A Misch; William R Berrington; James C Vary; Thomas R Hawn
Journal:  Microbiol Mol Biol Rev       Date:  2010-12       Impact factor: 11.056

7.  Carbohydrate-dependent binding of langerin to SodC, a cell wall glycoprotein of Mycobacterium leprae.

Authors:  Hee Jin Kim; Patrick J Brennan; Darragh Heaslip; Mark C Udey; Robert L Modlin; John T Belisle
Journal:  J Bacteriol       Date:  2014-11-24       Impact factor: 3.490

8.  Detection and quantification of Mycobacterium leprae in tissue samples by real-time PCR.

Authors:  Stefanie Kramme; Gisela Bretzel; Marcus Panning; Joseph Kawuma; Christian Drosten
Journal:  Med Microbiol Immunol       Date:  2003-07-22       Impact factor: 3.402

9.  High expression of myeloid-related proteins 8 and 14 characterizes an inflammatorily active but ineffective response of macrophages during leprosy.

Authors:  Cord H Sunderkötter; Jane Tomimori-Yamashita; Verena Nix; Solange M Maeda; Anca Sindrilaru; Mario Mariano; Clemens Sorg; Johannes Roth
Journal:  Immunology       Date:  2004-04       Impact factor: 7.397

Review 10.  Leprosy: a primer for Canadian physicians.

Authors:  Andrea K Boggild; Jay S Keystone; Kevin C Kain
Journal:  CMAJ       Date:  2004-01-06       Impact factor: 8.262

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