Literature DB >> 1003008

A quantitative dermatophyte infection model in the guinea pig--a parallel to the quantitated human infection model.

J H Greenberg, R D King, S Krebs, R Field.   

Abstract

A method is described for inducing quantitative dermatophyte infections in guinea pigs. This model is unique in that the epidermis in the infection site is not traumatized nor is it epilated. One hundred spore-inocula of Trichophyton mentagrophytes var. granulosum ATCC number 18748 induced infections in 85% of tested guinea pigs. The course of these infections in guinea pigs that had not had a previous infection (inexperienced) and those that had (experienced) paralleled that seen in experimental infections of human volunteers.

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Year:  1976        PMID: 1003008     DOI: 10.1111/1523-1747.ep12598588

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN: 0022-202X            Impact factor:   8.551


  11 in total

Review 1.  Generating and testing molecular hypotheses in the dermatophytes.

Authors:  Theodore C White; Brian G Oliver; Yvonne Gräser; Matthew R Henn
Journal:  Eukaryot Cell       Date:  2008-06-06

Review 2.  Relevant Animal Models in Dermatophyte Research.

Authors:  Ludivine Cambier; Marie-Pierre Heinen; Bernard Mignon
Journal:  Mycopathologia       Date:  2016-10-11       Impact factor: 2.574

3.  The inhibitory effect of PUVA on the immunity of experimental dermatophytosis in guinea pigs.

Authors:  T Okuwa; T Horio
Journal:  Arch Dermatol Res       Date:  1986       Impact factor: 3.017

4.  Suppression of in vitro lymphocyte transformation during an experimental dermatophyte infection.

Authors:  F Green; E Balish
Journal:  Infect Immun       Date:  1979-11       Impact factor: 3.441

5.  Cell-mediated immunity in experimental murine dermatophytosis. I. Temporal aspects of T-suppressor activity caused by Trichophyton quinckeanum.

Authors:  R A Calderon; R J Hay
Journal:  Immunology       Date:  1984-11       Impact factor: 7.397

Review 6.  Cutaneous defenses against dermatophytes and yeasts.

Authors:  D K Wagner; P G Sohnle
Journal:  Clin Microbiol Rev       Date:  1995-07       Impact factor: 26.132

7.  Dermatophyte virulence factors: identifying and analyzing genes that may contribute to chronic or acute skin infections.

Authors:  Rebecca Rashid Achterman; Theodore C White
Journal:  Int J Microbiol       Date:  2011-10-04

Review 8.  Animal model of dermatophytosis.

Authors:  Tsuyoshi Shimamura; Nobuo Kubota; Kazutoshi Shibuya
Journal:  J Biomed Biotechnol       Date:  2012-04-29

9.  HapX Mediates Iron Homeostasis in the Pathogenic Dermatophyte Arthroderma benhamiae but Is Dispensable for Virulence.

Authors:  Antje Kröber; Kirstin Scherlach; Peter Hortschansky; Ekaterina Shelest; Peter Staib; Olaf Kniemeyer; Axel A Brakhage
Journal:  PLoS One       Date:  2016-03-09       Impact factor: 3.240

Review 10.  Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.

Authors:  Patrick Van Dijck; Jelmer Sjollema; Bruno P Cammue; Katrien Lagrou; Judith Berman; Christophe d'Enfert; David R Andes; Maiken C Arendrup; Axel A Brakhage; Richard Calderone; Emilia Cantón; Tom Coenye; Paul Cos; Leah E Cowen; Mira Edgerton; Ana Espinel-Ingroff; Scott G Filler; Mahmoud Ghannoum; Neil A R Gow; Hubertus Haas; Mary Ann Jabra-Rizk; Elizabeth M Johnson; Shawn R Lockhart; Jose L Lopez-Ribot; Johan Maertens; Carol A Munro; Jeniel E Nett; Clarissa J Nobile; Michael A Pfaller; Gordon Ramage; Dominique Sanglard; Maurizio Sanguinetti; Isabel Spriet; Paul E Verweij; Adilia Warris; Joost Wauters; Michael R Yeaman; Sebastian A J Zaat; Karin Thevissen
Journal:  Microb Cell       Date:  2018-06-14
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