| Literature DB >> 1002761 |
R B Heppenstall, C W Goodwin, C T Brighton.
Abstract
Recent studies have demonstrated that fracture healing normally takes place under hypoxic conditions. The present study evaluated the effect of a state of chronic systemic hypoxia on fracture healing in dogs. A significant delay in fracture healing was demonstrated in the hypoxic animals roentgenographically, histologically, and by strength-testing criteria. A further reduction in the available oxygen supply below that present during normal repair had an adverse effect on fracture healing.Entities:
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Year: 1976 PMID: 1002761
Source DB: PubMed Journal: J Bone Joint Surg Am ISSN: 0021-9355 Impact factor: 5.284