Literature DB >> 10026443

Diagnosis of chronic pancreatitis and newer aspects of pain control.

C W Imrie1, N Menezes, C R Carter.   

Abstract

The diagnosis of chronic pancreatitis in the UK largely rests on the combination of the clinical presentation which usually features pain which is often provoked by food and/or alcohol. There is usually a 30 to 40-min delay between the stimulus and the pain and, after exclusion of other causes of pain, an ERCP is performed. A minority of patients will have pancreatic function tests carried out while increasingly the diagnosis is being made by MR scanning. The control of pain is often the most important aspect of management to the patient. In those with large ducts due to compression of focal areas of the duct system surgical by-pass therapy is indicated. There is a bigger problem in patients with small ducts and chronic pancreatitis in whom extensive resection may be inappropriate. Our experience with minimally invasive thoracoscopic splanchnicectomy has been encouraging over the last three years. Having previously tried both percutaneous coeliac ganglion block and surgical excision of this nerve tissue, it is a great deal easier to carry out this procedure which usually takes only 15-20 min per side. Patients are usually only admitted for 48 h and the immediate beneficial effect usually results in opiate analgesia being discontinued with considerable improvement in the quality of life. While there is a slight drop-off in benefit between 6 and 12 months post-operatively, the clinical effectiveness of this approach is to be commended and the author's experience will be presented to support this view.

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Year:  1999        PMID: 10026443     DOI: 10.1159/000051465

Source DB:  PubMed          Journal:  Digestion        ISSN: 0012-2823            Impact factor:   3.216


  3 in total

Review 1.  Surgical options in the patient with chronic pancreatitis.

Authors:  R H Bell
Journal:  Curr Gastroenterol Rep       Date:  2000-04

2.  Bilateral thoracoscopic splanchnicectomy for pain in patients with chronic pancreatitis impairs adrenomedullary but not noradrenergic sympathetic function.

Authors:  H C J L Buscher; J W M Lenders; O H G Wilder-Smith; C G J Sweep; H van Goor
Journal:  Surg Endosc       Date:  2012-03-07       Impact factor: 4.584

3.  Quality of life after bilateral thoracoscopic splanchnicectomy: long-term evaluation in patients with chronic pancreatitis.

Authors:  Thomas J Howard; John B Swofford; Dennis L Wagner; Stuart Sherman; Glen A Lehman
Journal:  J Gastrointest Surg       Date:  2002 Nov-Dec       Impact factor: 3.267

  3 in total

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