Literature DB >> 10026382

The prevalence, assessment and associations of falls in dementia with Lewy bodies and Alzheimer's disease.

C G Ballard1, F Shaw, K Lowery, I McKeith, R Kenny.   

Abstract

Falls were assessed for 3 months using a daily fall diary in 65 (30 dementia with Lewy bodies, DLB; 35 Alzheimer's disease, AD) dementia patients from a case register, diagnosed using operationalised clinical criteria, with established accuracy against post-mortem. Multiple falls (>5) occurred in 37% of DLB patients and 6% of those with AD, often resulting in injury. None of the standard risk assessment tools identified fallers, but they did identify multiple fallers. More detailed evaluation methods examining gait patterns, sway and neurovascular instability were not helpful. Multiple falls were associated with DLB, parkinsonism, previous falls, greater impairment of activities of daily living and older age. Falls are particularly common in DLB sufferers and may aid diagnosis. Treatment studies evaluating fall reduction strategies are a priority.

Entities:  

Mesh:

Year:  1999        PMID: 10026382     DOI: 10.1159/000017108

Source DB:  PubMed          Journal:  Dement Geriatr Cogn Disord        ISSN: 1420-8008            Impact factor:   2.959


  19 in total

Review 1.  Management of Gait Changes and Fall Risk in MCI and Dementia.

Authors:  Gilles Allali; Joe Verghese
Journal:  Curr Treat Options Neurol       Date:  2017-09       Impact factor: 3.598

Review 2.  Dementia with Lewy bodies: clinical features and treatment.

Authors:  S Campbell; S Stephens; C Ballard
Journal:  Drugs Aging       Date:  2001       Impact factor: 3.923

Review 3.  Activities of daily living in patients with dementia: clinical relevance, methods of assessment and effects of treatment.

Authors:  Abhilash K Desai; George T Grossberg; Dharmesh N Sheth
Journal:  CNS Drugs       Date:  2004       Impact factor: 5.749

4.  Falls, Cognitive Impairment, and Gait Performance: Results From the GOOD Initiative.

Authors:  Gilles Allali; Cyrille P Launay; Helena M Blumen; Michele L Callisaya; Anne-Marie De Cock; Reto W Kressig; Velandai Srikanth; Jean-Paul Steinmetz; Joe Verghese; Olivier Beauchet
Journal:  J Am Med Dir Assoc       Date:  2016-11-30       Impact factor: 4.669

Review 5.  Dementia with Lewy bodies. Review of diagnosis and pharmacologic management.

Authors:  Christopher Frank
Journal:  Can Fam Physician       Date:  2003-10       Impact factor: 3.275

6.  Carotid sinus syndrome is common in dementia with Lewy bodies and correlates with deep white matter lesions.

Authors:  R A Kenny; F E Shaw; J T O'Brien; P H Scheltens; R Kalaria; C Ballard
Journal:  J Neurol Neurosurg Psychiatry       Date:  2004-07       Impact factor: 10.154

7.  Dementia and hip fractures: development of a pathogenic framework for understanding and studying risk.

Authors:  Susan M Friedman; Isaura B Menzies; Susan V Bukata; Daniel A Mendelson; Stephen L Kates
Journal:  Geriatr Orthop Surg Rehabil       Date:  2010-11

8.  Do elderly people at more severe activity of daily living limitation stages fall more?

Authors:  John T Henry-Sánchez; Jibby E Kurichi; Dawei Xie; Qiang Pan; Margaret G Stineman
Journal:  Am J Phys Med Rehabil       Date:  2012-07       Impact factor: 2.159

Review 9.  Dementia with Lewy bodies: disease concept and genetics.

Authors:  Manuel B Graeber; Ulrich Müller
Journal:  Neurogenetics       Date:  2003-07-26       Impact factor: 2.660

10.  Incidence and prediction of falls in dementia: a prospective study in older people.

Authors:  Louise M Allan; Clive G Ballard; Elise N Rowan; Rose Anne Kenny
Journal:  PLoS One       Date:  2009-05-13       Impact factor: 3.240

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