Literature DB >> 10025966

Three receptor genes for plasminogen related growth factors in the genome of the puffer fish Fugu rubripes.

A Cottage1, M Clark, K Hawker, Y Umrania, D Wheller, M Bishop, G Elgar.   

Abstract

Plasminogen related growth factors (PRGFs) and their receptors play major roles in embryogenesis, tissue regeneration and neoplasia. In order to investigate the complexity and evolution of the PRGF receptor family we have cloned and sequenced three receptors for PRGFs in the teleost fish Fugu rubripes, a model vertebrate with a compact genome. One of the receptor genes isolated encodes the orthologue of mammalian MET, whilst the other two may represent Fugu rubripes orthologues of RON and SEA. This is the first time three PRGF receptors have been identified in a single species.

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Year:  1999        PMID： 10025966     DOI： 10.1016/s0014-5793(99)00011-3

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  7 in total

1.  Analyses of the extent of shared synteny and conserved gene orders between the genome of Fugu rubripes and human 20q.

Authors:  Sarah F Smith; Philip Snell; Frank Gruetzner; Anthony J Bench; Thomas Haaf; Judith A Metcalfe; Anthony R Green; Greg Elgar
Journal:  Genome Res       Date:  2002-05       Impact factor: 9.043

Review 2.  Bioinformatics methods to predict protein structure and function. A practical approach.

Authors:  Yvonne J K Edwards; Amanda Cottage
Journal:  Mol Biotechnol       Date:  2003-02       Impact factor: 2.695

Review 3.  Strategies of targeting the extracellular domain of RON tyrosine kinase receptor for cancer therapy and drug delivery.

Authors:  Omid Zarei; Silvia Benvenuti; Fulya Ustun-Alkan; Maryam Hamzeh-Mivehroud; Siavoush Dastmalchi
Journal:  J Cancer Res Clin Oncol       Date:  2016-08-08       Impact factor: 4.553

Review 4.  Met-related receptor tyrosine kinase Ron in tumor growth and metastasis.

Authors:  Purnima K Wagh; Belinda E Peace; Susan E Waltz
Journal:  Adv Cancer Res       Date:  2008       Impact factor: 6.242

Review 5.  Ron receptor tyrosine kinase signaling as a therapeutic target.

Authors:  Nancy M Benight; Susan E Waltz
Journal:  Expert Opin Ther Targets       Date:  2012-07-26       Impact factor: 6.902

6.  SAND, a new protein family: from nucleic acid to protein structure and function prediction.

Authors:  A Cottage; Y J Edwards; G Elgar
Journal:  Comp Funct Genomics       Date:  2001

7.  Estimation of synteny conservation and genome compaction between pufferfish (Fugu) and human.

Authors:  A McLysaght; A J Enright; L Skrabanek; K H Wolfe
Journal:  Yeast       Date:  2000-04       Impact factor: 3.239
  7 in total

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