BACKGROUND: Polymorphism in the serotonin transporter promoter gene has been recently reported to be associated with the personality trait known as anxiety-related traits. We have attempted to replicate these findings in 101 healthy Japanese subjects. METHODS: The personality traits of the subjects were assessed with the tridimensional personality questionnaire. RESULTS: An association was observed in the present study between individuals grouped according to the transporter gene and harm avoidance scores. CONCLUSIONS: These data supported that there was an association between the serotonin transporter gene and anxiety.
BACKGROUND: Polymorphism in the serotonin transporter promoter gene has been recently reported to be associated with the personality trait known as anxiety-related traits. We have attempted to replicate these findings in 101 healthy Japanese subjects. METHODS: The personality traits of the subjects were assessed with the tridimensional personality questionnaire. RESULTS: An association was observed in the present study between individuals grouped according to the transporter gene and harm avoidance scores. CONCLUSIONS: These data supported that there was an association between the serotonin transporter gene and anxiety.
Authors: Marcus R Munafò; Nelson B Freimer; Whitney Ng; Roel Ophoff; Juha Veijola; Jouko Miettunen; Marjo-Riitta Järvelin; Anja Taanila; Jonathan Flint Journal: Am J Med Genet B Neuropsychiatr Genet Date: 2009-03-05 Impact factor: 3.568
Authors: Beverly H Brummett; Stephen H Boyle; Ilene C Siegler; Cynthia M Kuhn; Allison Ashley-Koch; Charles R Jonassaint; Stephan Züchner; Ann Collins; Redford B Williams Journal: Behav Genet Date: 2007-10-23 Impact factor: 2.805