Literature DB >> 10021355

Cancer genetics: tumor suppressor meets oncogene.

E R Fearon1, C V Dang.   

Abstract

The adenomatous polyposis coli (APC) tumor suppressor protein is inactivated by mutations in the majority of colorectal cancers. A recent study has revealed that alterations in the APC signaling pathway can result in the transcriptional activation of the c-MYC gene.

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Year:  1999        PMID: 10021355     DOI: 10.1016/s0960-9822(99)80012-8

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  16 in total

1.  Quantitative mRNA expression analysis from formalin-fixed, paraffin-embedded tissues using 5' nuclease quantitative reverse transcription-polymerase chain reaction.

Authors:  T E Godfrey; S H Kim; M Chavira; D W Ruff; R S Warren; J W Gray; R H Jensen
Journal:  J Mol Diagn       Date:  2000-05       Impact factor: 5.568

Review 2.  Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy.

Authors:  Jiao Zhang; Yan-Hua Chen; Qun Lu
Journal:  Future Oncol       Date:  2010-04       Impact factor: 3.404

3.  Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis.

Authors:  Lior Golomb; Debora Rosa Bublik; Sylvia Wilder; Reinat Nevo; Vladimir Kiss; Kristina Grabusic; Sinisa Volarevic; Moshe Oren
Journal:  Mol Cell       Date:  2012-01-27       Impact factor: 17.970

4.  Expression and somatic mutations of SDHAF2 (SDH5), a novel endocrine tumor suppressor gene in parathyroid tumors of primary hyperparathyroidism.

Authors:  Lee F Starker; Alberto Delgado-Verdugo; Robert Udelsman; Peyman Björklund; Tobias Carling
Journal:  Endocrine       Date:  2010-10-23       Impact factor: 3.633

5.  CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer.

Authors:  Mark L McCleland; Kathryn Mesh; Edward Lorenzana; Vivek S Chopra; Ehud Segal; Colin Watanabe; Benjamin Haley; Oleg Mayba; Murat Yaylaoglu; Florian Gnad; Ron Firestein
Journal:  J Clin Invest       Date:  2016-01-11       Impact factor: 14.808

6.  BRAF mutations in aberrant crypt foci and hyperplastic polyposis.

Authors:  Robyn Beach; Annie On-On Chan; Tsung-Teh Wu; Jill A White; Jeffrey S Morris; Simon Lunagomez; Russell R Broaddus; Jean-Pierre J Issa; Stanley R Hamilton; Asif Rashid
Journal:  Am J Pathol       Date:  2005-04       Impact factor: 4.307

7.  Induction of growth cessation by acacetin via β-catenin pathway and apoptosis by apoptosis inducing factor activation in colorectal carcinoma cells.

Authors:  Nupoor Prasad; Jiten R Sharma; Umesh C S Yadav
Journal:  Mol Biol Rep       Date:  2019-11-16       Impact factor: 2.316

8.  CpG island methylation in colorectal adenomas.

Authors:  A Rashid; L Shen; J S Morris; J P Issa; S R Hamilton
Journal:  Am J Pathol       Date:  2001-09       Impact factor: 4.307

9.  Concordant CpG island methylation in hyperplastic polyposis.

Authors:  Annie On-On Chan; Jean-Pierre J Issa; Jeffrey S Morris; Stanley R Hamilton; Asif Rashid
Journal:  Am J Pathol       Date:  2002-02       Impact factor: 4.307

10.  Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate.

Authors:  Lizhong Wang; Runhua Liu; Weiquan Li; Chong Chen; Hiroto Katoh; Guo-Yun Chen; Beth McNally; Lin Lin; Penghui Zhou; Tao Zuo; Kathleen A Cooney; Yang Liu; Pan Zheng
Journal:  Cancer Cell       Date:  2009-10-06       Impact factor: 31.743

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