Literature DB >> 1002121

Bioavailability and LH-suppressing effect of different testosterone preparations in normal and hypogonadal men.

E Nieschlag, H J Cüppers, W Wiegelmann, E J Wickings.   

Abstract

The therapeutic effectiveness of intramuscularly administered testosterone esters and free testosterone in suppositories was investigated by the measurement of plasma testosterone and LH levels after administration to normal and hypogonadal men. Testosterone levels were elevated above the lower physiological limit for 1 day after 25 mg testosterone one propionate, for 2 days after 50 mg testosterone propionate and for 14 days after 250 mg testosterone oenanthate. LH levels were suppressed for the corresponding periods. Elevated plasma testosterone and suppressed LH levels were maintained by testosterone suppositories (3 x 20 mg for 5 days).

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Year:  1976        PMID： 1002121     DOI： 10.1159/000178721

Source DB:  PubMed          Journal:  Horm Res        ISSN： 0301-0163


  10 in total

Review 1.  Optimisation of treatment by applying programmable rate-controlled drug delivery technology.

Authors:  Yie W Chien; Senshang Lin
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

2.  [Testosterone replacement: application and surveillance].

Authors:  G Popken
Journal:  Urologe A       Date:  2010-01       Impact factor: 0.639

Review 3.  The Roles of Androgens in Humans: Biology, Metabolic Regulation and Health.

Authors:  Marià Alemany
Journal:  Int J Mol Sci       Date:  2022-10-08       Impact factor: 6.208

4.  Pubertal induction and transition to adult sex hormone replacement in patients with congenital pituitary or gonadal reproductive hormone deficiency: an Endo-ERN clinical practice guideline.

Authors:  A Nordenström; S F Ahmed; E van den Akker; J Blair; M Bonomi; C Brachet; L H A Broersen; H L Claahsen-van der Grinten; A B Dessens; A Gawlik; C H Gravholt; A Juul; C Krausz; T Raivio; A Smyth; P Touraine; D Vitali; O M Dekkers
Journal:  Eur J Endocrinol       Date:  2022-04-21       Impact factor: 6.558

Review 5.  Androgen replacement therapy: present and future.

Authors:  Louis J G Gooren; Mathijs C M Bunck
Journal:  Drugs       Date:  2004       Impact factor: 9.546

6.  Beneficial effects of testosterone therapy on functional capacity, cardiovascular parameters, and quality of life in patients with congestive heart failure.

Authors:  Ahmad Mirdamadi; Mohammad Garakyaraghi; Ali Pourmoghaddas; Alireza Bahmani; Hamideh Mahmoudi; Mojgan Gharipour
Journal:  Biomed Res Int       Date:  2014-07-06       Impact factor: 3.411

Review 7.  Testosterone in men with hypogonadism and transgender males: a systematic review comparing three different preparations.

Authors:  Milou Cecilia Madsen; Martin den Heijer; Claudia Pees; Nienke R Biermasz; Leontine E H Bakker
Journal:  Endocr Connect       Date:  2022-07-25       Impact factor: 3.221

Review 8.  Safety and efficacy of testosterone gel in the treatment of male hypogonadism.

Authors:  Kishore M Lakshman; Shehzad Basaria
Journal:  Clin Interv Aging       Date:  2009-11-18       Impact factor: 4.458

9.  Incidence and Factors Associated With Acne Among Transgender Patients Receiving Masculinizing Hormone Therapy.

Authors:  Nick Thoreson; Jason A Park; Chris Grasso; Jennifer Potter; Dana S King; Linda G Marc; Changyu Shen; J Klint Peebles; Erica D Dommasch
Journal:  JAMA Dermatol       Date:  2021-03-01       Impact factor: 10.282

Review 10.  Testosterone for the aging male; current evidence and recommended practice.

Authors:  Roger D Stanworth; T Hugh Jones
Journal:  Clin Interv Aging       Date:  2008       Impact factor: 4.458
  10 in total

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