Olfactory neuroblastomas: a clinicopathologic study.

Clinical and pathologic findings in seven patients with olfactory neuroblastomas are reviewed. Thes neoplasms occurred over a wide age range and, regardless of microscopic pattern, had an unpredictable clinical course. Total extirpation followed by radiation provided optimal therapeutic benefit. The difficulty of pathologic diagnosis of olfactory neuroblastomas is emphasized by the number of neoplasms excluded from this series after critical review of clinical and microscopic findings.